Powered exoskeletons have the potential to improve measures of ambulation for clinical populations. However, challenges exist integrating the actuators, braces, and power electronics into a lightweight usable technology, particularly because adding mass to an individual changes ambulation mechanics and increases human energy consumption. If not designed correctly, wearable exoskeletons make ambulation activities more difficult. To address this limitation, we design and evaluate active and passive transmission systems that can operate across multiple speed-torque power domains enabling lighter, more-efficient acuators and powered wearable robots.